Muscular Dystrophy Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You have been confirmed through genetic testing to have FSHD2, meaning you have a specific change in the SMCHD1 gene and a related genetic feature called a D4Z4 4qA allele
• You are between 18 and 75 years old
• You have noticeable muscle weakness in your arms or legs
• Your disease falls within a certain range of severity (called a RICCI score of 2 to 5) — either you can still walk (score 2–4) or you can no longer walk (score 5)
• You are willing to give written consent to take part after receiving information about the study
• You are covered by a social security/health insurance system
• If you currently take any over-the-counter supplements, you are willing to keep taking them at the same level throughout the study

Who may not be able to join:

• You have another health condition (unrelated to FSHD2) that could affect how your disease progresses or make testing unsafe, in the opinion of the study doctor
• You regularly use certain muscle-affecting medications such as steroids, oral testosterone or similar drugs, or oral beta agonists
• You have a reason why you cannot safely have a muscle MRI scan
• You have travelled to a tropical or subtropical country in the last 3 months
• You have exercised within 10 hours before your blood test appointment
• You have not fasted (gone without food) for at least 10 hours before your blood test
• You are following a special diet for medical reasons prescribed by a doctor or dietitian
• You regularly drink large amounts of alcohol
• You have used an illegal recreational drug in the last 3 months
• You have received a vaccine in the last 3 months
• You have received a blood transfusion or immunoglobulins (a type of antibody treatment) in the last 3 months
• You have tested positive for HIV, Hepatitis B (HBV), or Hepatitis C (HCV)
• You have had an infection in the 3 weeks before your study visit
• You have taken an experimental drug in an FSHD clinical trial within the last 30 days
• You are currently taking part in another clinical trial
• You are pregnant, breastfeeding, or able to become pregnant and not using contraception
• You are under a legal protection order or guardianship arrangement as defined under French law (confirm with trial site)
• You do not wish to take part or have expressed that you do not want to participate

Important: Always verify eligibility with the trial site directly before applying.