Head and Neck Cancer Trial, Recruiting NCT06080503 Sponsor: University of Texas Southwestern Medical Center Condition: Head and Neck Cancer
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Head and Neck Cancer Trial, Recruiting

NCT06080503
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed through laboratory testing with a specific type of throat cancer (squamous cell carcinoma or a related variant) located in the voice box (glottis).
  • People whose cancer is classified as stage 0, I, or II (meaning it has not spread beyond the voice box), confirmed by a camera examination of the throat and imaging scans showing no signs of cancer in nearby lymph nodes.
  • People who are 18 years of age or older.
  • People who are generally able to carry out daily activities, with only mild limitations at most (this is measured on a standard medical scale — confirm with trial site).
  • Women who could potentially become pregnant, and men, must be willing to use reliable contraception during the trial and for 90 days after treatment ends. This applies to women who have not had their uterus or both ovaries removed, and who have had a menstrual period at any point in the past 12 months.
  • People who are able to understand the study information and are willing to sign a consent form.

Who may not be able to join:

  • People whose larynx cancer is classified as stage III or stage IV.
  • People whose cancer has spread to a specific part of the voice box cartilage beyond a defined boundary (confirm with trial site).
  • People who have previously received chemotherapy to treat this particular throat cancer.
  • People who have another separate cancer present at the same time in the head or neck area.
  • People who have previously had radiation therapy in the same area of the body in a way that would overlap with the radiation planned in this trial.
  • People who currently smoke more than one pack of cigarettes per day.
  • People who are currently taking part in another clinical trial involving an experimental treatment.
  • People with serious uncontrolled health conditions, such as an active infection, uncontrolled heart failure, unstable chest pain, irregular heart rhythm, or a mental health or personal situation that may make it difficult to follow the trial requirements.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: David Sher, MD, MPH, University of Texas Southwestern Medical Center

Phone: 214-645-2465

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
14 March 2024
Est. completion
1 November 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

To compare the acute toxicity outcomes between patients treated with highly-conformal hypofractionated radiotherapy and conventional radiotherapy.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov