PTSD Trial, Recruiting NCT06096740 Sponsor: University of Texas at Austin Condition: PTSD
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PTSD Trial, Recruiting

NCT06096740
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • English is your main language, and you can understand instructions given by the research team.
  • You have been diagnosed with PTSD (caused by a traumatic event you experienced), and your symptoms have been present for at least 3 months, confirmed through a professional assessment.
  • You are able and willing to have a brain scan called an fMRI (a non-invasive scan that uses magnets, not radiation).
  • You are willing to take part in multiple assessments over time, which may include being in a group that waits before receiving treatment.

Who may not be able to join:

  • You have a current or past history of psychosis or bipolar disorder, based on what you report or a clinical interview.
  • You have had a significant problem with substance dependence (such as alcohol or drugs) in the past 6 months.
  • You currently take regular psychiatric medications (such as antidepressants), unless your only medication is a short-acting anxiety or pain medication taken no more than three times a week on average, or a short-acting ADHD medication that can be skipped the day of a study visit.
  • You have made a suicide attempt in the past 6 months, or you currently have thoughts of suicide with intent to act.
  • You have metal permanently fixed inside your body that cannot be removed (because of the MRI scanner).
  • You have a history of certain brain or nervous system conditions, including stroke, epilepsy, seizures (other than fever-related seizures in childhood), brain surgery, brain tumour or bleeding, electroconvulsive therapy, radiation to the brain, or thyroid disorder.
  • You are currently pregnant or trying to become pregnant.
  • You are currently receiving, or have received in the past year, more than 3 sessions of a talking therapy that includes exposure therapy or restructuring negative thoughts.
  • You have previously received or are currently receiving ketamine, esketamine, or any form of brain stimulation treatment (confirm with trial site).
  • You are currently receiving another treatment that could interfere with the study results.
  • You have had a penetrating head injury or severe traumatic brain injury (note: mild-to-moderate brain injury without a penetrating wound may still be allowed — confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Gregory A Fonzo, PhD, The University of Texas at Austin

Phone: 512-495-5856

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
University of Texas at Austin
Registry
ClinicalTrials.gov
Start date
1 June 2024
Est. completion
1 March 2029

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Within subject beta coefficients for each parametrically modulated regressor of the Reinforcement Learning Task with Threat

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov