Phase 2 Rare Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People between 21 and 49 years of age (including those ages)
• People who have used cannabis at least once in their life, but no more than three days in the past 30 days before joining
• People who are able to sign a consent form agreeing to take part
• People who are willing to follow the study's procedures and requirements
• People whose lung function test result (measuring how much air can be breathed out in one second) is at or below 90% of the expected level
• People who can communicate and understand English or French
• Female participants who cannot become pregnant — either due to being postmenopausal (no periods for 12 months and aged 45 or older) or having had a documented surgical procedure such as tubal ligation, hysterectomy, or removal of both ovaries
• Female participants who could become pregnant but have a negative pregnancy test at the start and follow-up visits, have no plans to become pregnant during the study, and agree to use an accepted form of birth control throughout the study

Who may not be able to join:

• People with a serious medical condition that, in the study doctor's opinion, makes safe participation or giving fully informed consent impossible
• People with a history of schizophrenia, schizoaffective disorder, or bipolar disorder, or who are currently experiencing acute psychosis, mania, or suicidal thoughts (as assessed by a standard psychiatric interview)
• People with any other serious, unstable, or acute mental health condition that, in the study doctor's opinion, makes safe participation or giving fully informed consent impossible
• People with known chronic liver disease, or whose liver enzyme levels (AST/ALT) are more than twice the normal upper limit at the screening visit
• People with blood pressure higher than 130/80 mmHg
• People with kidney disorders
• People with bleeding disorders
• People with a current moderate or severe substance use disorder (other than nicotine), as assessed by a standard clinical interview
• People who are currently pregnant, breastfeeding, or planning to become pregnant during the study
• People with pending legal matters or other circumstances that, in the study doctor's opinion, might prevent them from completing the study
• People who have taken any medication within 7 days before the experimental sessions that the study investigator believes may interact with cannabis
• People who have taken part in another clinical study involving cannabis or cannabinoids within the 30 days before being assigned to a study group
• People with a resting heart rate above 100 beats per minute
• People with a body mass index (BMI — a measure of body weight relative to height) above 29.9
• People with any significant abnormality found on a heart tracing (ECG) test at the screening visit

Important: Always verify eligibility with the trial site directly before applying.