Phase 1 Bladder Cancer Trial, Recruiting NCT06108492 Sponsor: Shanghai Hengrui Pharmaceutical Co., Ltd. Condition: Bladder Cancer
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Phase 1 Bladder Cancer Trial, Recruiting

NCT06108492
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You must be willing to take part voluntarily and sign a consent form agreeing to participate
  • You must be 18 years of age or older (any sex)
  • You must have previously had a tissue sample (biopsy) confirming you have intermediate or high-risk non-muscle-invasive bladder cancer (a type of bladder cancer that has not spread deep into the bladder wall)
  • You must be generally well enough to carry out daily activities with little or no limitation (confirm with trial site)
  • Your doctors expect you to live for at least 2 more years
  • Your blood counts and organ function (such as liver and kidneys) must be at an acceptable level (confirm with trial site)

Who may not be able to join:

  • You have had bladder surgery (such as TURBT) or radiation treatment within the 2 weeks before starting the trial
  • You are currently taking part in another clinical trial, or finished one less than 4 weeks before this trial would begin
  • You have a history of serious heart or stroke-related conditions
  • You have had a severe infection in the 2 weeks before starting the trial
  • You still have significant side effects from a previous cancer treatment that have not mostly cleared up (confirm with trial site)
  • You have had major surgery or a serious injury within the 4 weeks before starting the trial
  • You have previously received certain types of immune-based cancer therapies known as TNFR agonist antibodies (such as OX40, CD137, CD27, or CD357 antibodies)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 0518-82342973

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
Shanghai Hengrui Pharmaceutical Co., Ltd.
Registry
ClinicalTrials.gov
Start date
28 November 2023
Est. completion
31 December 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Incidence of dose limiting toxicities (DLTs); Maximum tolerated dose (MTD); Incidence and severity of adverse events (AEs) ([CTCAE] v5.0); RP2D(Recommended Phase 2 dose)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov