Phase 2 Lupus Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You are between 18 and 65 years old
- You have been diagnosed with Systemic Lupus Erythematosus (SLE, or "lupus") based on recognised medical guidelines
- A specific blood test (looking for certain antibodies linked to lupus) came back positive at the screening stage
- If joining as a lupus kidney disease (lupus nephritis) participant: you have active lupus nephritis confirmed by a kidney biopsy, classified as a specific type (Class III or IV, with or without Class V) (confirm with trial site)
- If joining as a non-kidney lupus participant: you have active lupus that is considered moderate to severe
Who may not be able to join:
- You have a medical reason why a procedure to collect white blood cells from your blood (called leukapheresis) would not be safe for you
- You have had a serious or life-threatening allergic reaction in the past to certain medicines called fludarabine or cyclophosphamide
- You currently have an active infection that requires medical treatment
- You have severe, worsening, or poorly controlled disease affecting the kidneys, liver, blood, gut, lungs, mental health, heart, or nervous system, including serious infections like blood poisoning
- You have other health conditions that the trial doctor believes could put you at unacceptable risk, affect the trial results, or interfere with trial procedures
- If applying as a lupus nephritis participant: you have kidney disease caused by something other than lupus
- You have previously received a type of treatment called CAR T cell therapy
- You have previously had a transplant of a solid organ (such as heart, liver, kidney, or lung) or a bone marrow/stem cell transplant
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Medical Director, Cabaletta Bio
Phone: 267 759 3100
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
To evaluate incidence of adverse events
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.