Phase 2 Leukaemia Trial, Recruiting NCT06138990 Sponsor: ETH Zurich Condition: Leukaemia
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Phase 2 Leukaemia Trial, Recruiting

NCT06138990
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have acute myeloid leukemia (AML) that has come back or has not responded to previous treatment, based on specific 2022 medical guidelines
  • People aged 18 to 70 years
  • People whose overall health means doctors consider them able to tolerate intensive (strong) chemotherapy
  • People who are willing and able to provide written consent to participate

Who may not be able to join:

  • People who have a specific type of leukemia called acute promyelocytic leukemia (APL), which involves particular genetic changes in the blood cells
  • People whose leukemia developed as a progression of a different blood cancer called chronic myeloid leukemia (CML)
  • People whose health means doctors consider them unable to tolerate intensive chemotherapy
  • People whose condition requires immediate treatment and cannot wait for a specific laboratory test (called PCY) to produce results
  • People whose blood sample did not meet the required quality standards for the PCY laboratory test
  • People with serious medical, psychiatric, psychological, family, or practical circumstances that, in the lead doctor's judgment, could interfere with the trial or make participation difficult
  • People who are legally unable to make their own decisions or who do not have the capacity to give informed consent
  • People who have taken part in another clinical trial involving an experimental drug within the 30 days before joining, or who are currently in another such trial

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Alexandre Theocharides, MD PhD, University of Zurich

Phone: +41 44 633 71 49

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
ETH Zurich
Registry
ClinicalTrials.gov
Start date
2 September 2024
Est. completion
30 June 2026

Where this trial is recruiting

🇨🇭 Switzerland

Primary endpoints

Complete response (CR) rate at day 28

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov