Phase 3 Brain Cancer Trial, Recruiting NCT06159335 Sponsor: University of Wisconsin, Madison Condition: Brain Cancer
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Phase 3 Brain Cancer Trial, Recruiting

NCT06159335
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 18 years or older
  • People who are able and willing to give their formal consent to take part in the study
  • People who have been diagnosed with brain metastases (cancer that has spread to the brain) and have at least one visible affected area showing up on a brain MRI scan with contrast dye
  • People who have received radiation therapy to the brain at some point in the last 2 years
  • People who are currently receiving, or have received in the past 6 months, another type of systemic treatment alongside radiation — such as immunotherapy, targeted therapy, or chemotherapy
  • People whose most recent standard MRI scan has raised uncertainty about whether changes in the brain represent cancer returning or are the result of previous treatment — this concern may have been raised by a radiologist, a specialist team, or a treating doctor based on symptoms or changing exam findings
  • People who are able to lie still for 30 to 60 minutes during the imaging procedure
  • People who are willing and able to undergo a PET/MRI or PET/CT scan
  • People who take a mild anti-anxiety tablet by mouth before imaging may still be considered eligible, provided that: the prescription for that medication belongs to the patient themselves; consent to participate in the study is given before taking the medication; and the patient attends the visit with a driver

Who may not be able to join:

  • People who are unable or unwilling to give formal consent to participate
  • People who are pregnant
  • People who have a medical reason preventing them from undergoing a PET/MRI or PET/CT scan
  • People with a known allergy to the imaging agent used in this study, called 18F-Fluciclovine, or any of its ingredients
  • People who would need intravenous (IV) sedation in order to undergo imaging

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Michael Veronesi, MD, PhD, University of Wisconsin, Madison

Phone: 608-282-8349

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Registry
ClinicalTrials.gov
Start date
10 January 2024
Est. completion
1 June 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Amino acid uptake into tumor tissue

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov