Phase 2 Melanoma Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been diagnosed with advanced melanoma
• People who have at least one tumour that can be measured on a scan
• People whose general health and ability to carry out daily activities is rated as good or mostly independent (ECOG score of 0 or 1)
• People whose doctors expect them to live for more than 12 weeks
• People whose blood and other lab test results meet the trial's required levels (confirm with trial site for specific values)
• Women who could become pregnant must have a negative pregnancy test within 7 days before the first dose, and must use effective contraception from signing the consent form until at least 6 months after the last dose
• Men who could father a child must use effective contraception from signing the consent form until at least 6 months after the last dose, and must agree not to donate sperm during that time
• People who understand the trial, are willing to sign the consent form, and are able to follow all trial requirements

Who may not be able to join:

• People who have received other cancer treatments within a certain period before the trial starts (confirm with trial site for specific timeframe)
• People who have had another type of cancer within a certain period before the trial starts (confirm with trial site for specific timeframe)
• People who have a history of, or currently have, serious heart or blood vessel conditions
• People who currently have an ongoing infection that requires treatment through a drip (intravenous antibiotics or antiviral medication)
• People who have an autoimmune disease, or have had one in the past (where the immune system attacks the body's own tissues)
• People who have a known mental health condition that might make it difficult to follow the trial's requirements
• People who have a build-up of fluid around the lungs, heart, or abdomen that needs to be drained, or who had such drainage within a set period before joining the trial (confirm with trial site for specific timeframe)
• People who need ongoing treatment with anti-herpes virus (anti-HSV) medication during the trial period
• People who have received a live or weakened (attenuated) vaccine within a certain period before the trial starts, plan to receive one during the trial, or have ever received any cancer vaccine in the past
• People who had major surgery within a set period before the trial starts and have not fully recovered, or who plan to have major surgery during the trial (confirm with trial site for specific timeframe)
• People who have had a history of drug use, drug abuse, or alcohol abuse in the year before signing the consent form
• Women who are pregnant, breastfeeding, or planning to become pregnant or have children during the trial
• People whose doctor leading the trial considers them unsuitable for any other reason

Important: Always verify eligibility with the trial site directly before applying.