Cardiomyopathy Trial, Recruiting NCT06214507 Sponsor: Rocket Pharmaceuticals Inc. Condition: Cardiomyopathy
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Cardiomyopathy Trial, Recruiting

NCT06214507
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

For people joining the prospective (forward-looking) group:

  • A certified genetic testing laboratory has confirmed a harmful or likely harmful change in the LAMP2 gene
  • The patient, or their parent or legal guardian, is able and willing to sign a consent form
  • The person is aged 8 years or older at the time of joining the trial
  • For females only: there is evidence of thickening of the heart's left pumping chamber, recorded within the 12 months before or at the time of joining

For people joining the retrospective (records-based) group:

  • A certified genetic testing laboratory has confirmed a harmful or likely harmful change in the LAMP2 gene
  • The patient, or their parent or legal guardian, is able and willing to sign a consent form as required by local rules
  • The person is aged 8 years or older at the time of joining the trial
  • The person has previously had a heart transplant or previously had a mechanical device used to help their heart pump
  • At least 30 days of past medical records are available from before the heart transplant or mechanical heart support
  • For females only: there is past evidence of thickening of the heart's left pumping chamber

Who may not be able to join:

  • People who are currently enrolled in another clinical trial that uses an experimental treatment for any condition, where that involvement could affect the results of this study
  • People who have previously received a gene therapy treatment
  • For the prospective group only: people who have already had a mechanical heart-assist device implanted at the time of joining
  • For the prospective group only: people who have already had a heart transplant at the time of joining
  • For females only: people who are older than 51 years of age at the time of joining

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 646-627-0033

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Rocket Pharmaceuticals Inc.
Registry
ClinicalTrials.gov
Start date
20 December 2023
Est. completion
1 December 2029

Where this trial is recruiting

🇩🇪 Germany 🇮🇱 Israel 🇮🇹 Italy 🇪🇸 Spain 🇬🇧 United Kingdom 🇺🇸 United States

Primary endpoints

Left Ventricular Mass Index (LVMI) by echocardiogram

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov