Phase 1 Interstitial Lung Disease Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are between 40 and 75 years old (any gender)
• You have been diagnosed with IPF (idiopathic pulmonary fibrosis) according to specific 2022 medical guidelines
• Your IPF has been considered stable by your doctor for the past 3 months, and your lung function test results fall within certain specific ranges (confirm with trial site)
• You have been receiving standard treatment for IPF for at least 3 months and have stayed on that treatment consistently
• You are willing and able to follow the trial's requirements, complete breathing/lung function tests, and sign a consent form

Who may not be able to join:

• You are allergic to any ingredient in the trial treatment
• You have a lung condition other than IPF, such as another type of interstitial lung disease, a lung disease caused by chemicals, drugs, or workplace exposure, a granuloma-related lung disease, or you have had part of a lung surgically removed
• You currently have or have had asthma, a blood clot in the lungs, a collapsed lung, lung cancer, or an active lung disease; or you have a history of immune system disorders, an immune deficiency condition, or an organ transplant
• Your recent chest scan (HRCT) shows that the area of air-trapping (emphysema) in your lungs is larger than the area of scarring (fibrosis)
• You have previously received stem cell therapy, or you are unable to tolerate cell-based treatments
• Your standard IPF treatment has not been stable in the 3 months before the screening period
• You have taken certain immune-suppressing or immune-modifying medications (such as Mycophenolate Mofetil, cyclophosphamide, tacrolimus, JAK inhibitors, or certain Chinese herbal medicines) in the past 3 months
• You have received certain biologic medications (such as rituximab or specific monoclonal antibodies) in the past 6 months
• You have taken certain other medications including blood thinners or specific drugs used for IPF within the past 4 weeks (confirm with trial site for full list)
• You have taken part in another interventional clinical trial recently (within 3 months or longer, depending on the drug involved)
• You have been hospitalised 2 or more times in the past year due to a sudden worsening of your IPF
• You have had a lung infection in the past month
• You have previously needed a breathing machine (ventilator), or you currently need to use supplemental oxygen for more than 15 hours per day
• You have smoked in the past 3 months, or you are unwilling or unable to stop smoking during the trial
• Your doctor believes your life expectancy may be less than 1 year
• Your blood test results fall outside certain acceptable ranges for blood cell counts, liver function, kidney function, or other markers (confirm with trial site for specific values)
• You currently have serious conditions affecting your heart, kidneys, liver, blood, nervous system, or other body systems — for example, severe heart failure, poorly controlled high blood pressure, severe kidney disease requiring dialysis, or advanced liver disease
• You have or have had any type of cancer (malignant tumour)
• Your heart tracing (ECG/electrocardiogram) shows certain serious heart rhythm problems
• You test positive for hepatitis B surface antigen, hepatitis C antibodies, HIV antibodies, or syphilis — though some people with hepatitis B or cured hepatitis C may still be considered eligible (confirm with trial site)
• You are pregnant, breastfeeding, or have a positive pregnancy test; or you (male or female) are of childbearing potential and are unwilling or unable to use effective non-hormonal contraception during the trial and for 6 months after it ends
• The investigator (trial doctor) decides for any other reason that the trial is not appropriate for you

Important: Always verify eligibility with the trial site directly before applying.