Phase 2 Thyroid Cancer Trial, Recruiting NCT06239194 Sponsor: ModeX Therapeutics, An OPKO Health Company Condition: Thyroid Cancer
Back to Thyroid Cancer

Phase 2 Thyroid Cancer Trial, Recruiting

NCT06239194
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You must be 18 years of age or older
  • Your cancer must be a solid tumor that has spread to other parts of the body, confirmed by a tissue or cell sample test
  • You must be fairly active and able to care for yourself, with only minor limitations on physical activity (confirm with trial site regarding exact fitness level required)
  • You must have at least one area of cancer that can be measured on a scan
  • You must be willing to use an approved form of contraception during the study, in line with local guidelines
  • Your blood counts, liver, and kidney must be working well enough to meet the study's requirements
  • You must be able to understand and sign a consent form agreeing to participate

Who may not be able to join:

  • People with significant heart problems or heart disease
  • People who still have unresolved side effects from previous cancer treatments
  • People who have had an organ transplant or bone marrow/blood cell transplant in the past
  • People who have brain metastases (cancer that has spread to the brain) that are untreated or not under control
  • People who are HIV positive, or have active hepatitis B or C, or have an ongoing infection that requires IV treatment
  • People who have received a live vaccine within 28 days before the planned start of treatment
  • People who the study doctor feels are not suitable to participate, for any medical or other reason
  • People who are currently taking part in another clinical trial during the treatment period
  • People with a known allergy to the study drug MDX2001 or any of its components
  • People who need supplemental oxygen for everyday activities

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: (857) 233-9936

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
ModeX Therapeutics, An OPKO Health Company
Registry
ClinicalTrials.gov
Start date
12 June 2024
Est. completion
1 August 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

All Phases: Adverse events (AEs); Phase 1b and Phase 2a: Objective response rate of MDX2001; Phase 1: Recommended Phase 2 dose (RP2D)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov