Phase 2 Lung Cancer Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are willing and able to sign a consent form agreeing to take part in the study.
• People aged 18 years or older.
• People who have been diagnosed with small cell lung cancer (SCLC) through a tissue or cell sample, and whose cancer has been confirmed as limited stage (not spread widely) through imaging scans such as CT or PET-CT.
• People with a good general level of physical functioning, rated 0 or 1 on a standard medical scale (meaning largely able to carry out daily activities with little or no restriction).
• People with a life expectancy of at least 12 weeks.
• People who have at least one measurable tumour as assessed by standard imaging criteria.
• People whose liver, kidneys, and blood system are functioning well enough to participate.
• People whose cancer has not spread to other parts of the body.
• People whose cancer is expected to be able to be completely removed by surgery.
• People whose lung function is strong enough to tolerate a surgical procedure.
• Women who are able to become pregnant must use effective contraception throughout the study and for at least 120 days after the last chemotherapy or last dose of the study drug (whichever comes later), and must have a negative pregnancy test within 7 days before joining.
• Men who have not had a sterilisation procedure must use effective contraception throughout the study and for at least 120 days after the last chemotherapy or last dose of the study drug (whichever comes later).

Who may not be able to join:

• People who have previously received any cancer treatment for a thymic epithelial tumour, including surgery, radiation, chemotherapy, targeted therapy, or experimental treatment.
• People who have had a different type of cancer (other than SCLC) within the five years before the start of this trial.
• People with serious or unstable health conditions, including active infection, uncontrolled high blood pressure, recent or ongoing chest pain (angina), moderate-to-severe heart failure, a heart attack within the past six months, serious irregular heartbeat requiring medication, or significant liver, kidney, or metabolic disease.
• People with an active or suspected autoimmune disease, or a nerve or muscle condition related to cancer affecting the immune system, that requires ongoing systemic treatment.
• People who have a known allergy to the study drug or any of its ingredients.
• People who currently have interstitial lung disease (a condition causing scarring or inflammation in the lungs).
• People with active hepatitis B, hepatitis C, or HIV.
• People who are pregnant or currently breastfeeding.
• People who have difficulty absorbing food or nutrients normally (confirm with trial site).
• People with neurological or psychiatric conditions that would make it difficult to cooperate with the study.
• People whom the trial investigators consider unsuitable for any other reason.

Important: Always verify eligibility with the trial site directly before applying.