Phase 4 Chronic Kidney Disease Trial, Recruiting NCT06256991 Sponsor: University Medical Center Groningen Condition: Chronic Kidney Disease
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Phase 4 Chronic Kidney Disease Trial, Recruiting

NCT06256991
Recruiting Phase 4

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults aged 18 or older.
  • People with moderate-to-severe chronic kidney disease, specifically a kidney function level (eGFR) between 15 and 44 mL/min/1.73 m².
  • People who have protein in their urine above certain measured levels (confirm with trial site for exact values).
  • People with a systolic (top number) blood pressure above 130 mmHg, or who are already taking one or more blood pressure-lowering medications.
  • People with a blood potassium level between 4.0 and 5.0 mmol/L at the time of assessment.
  • People currently taking a less-than-maximum prescribed dose of a type of blood pressure medication known as an ACE inhibitor or ARB.

Who may not be able to join:

  • People whose ACE inhibitor or ARB dose was reduced in the past year because their kidney function dropped significantly (by more than 25%).
  • People who had a dangerously high potassium level (above 6.0 mmol/L) in the past year.
  • People who are pregnant or breastfeeding.
  • People with a life expectancy of less than 12 months.
  • People currently taking lithium, potassium-sparing water tablets (diuretics), potassium supplements, trimethoprim (an antibiotic), or anti-inflammatory pain medications (NSAIDs such as ibuprofen).
  • People who have received a kidney transplant, or who have been diagnosed with a genetic kidney condition called autosomal dominant polycystic kidney disease, or certain other types of non-glomerular kidney disease (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 13 July 2026
Phase 4 trials study a drug that has already been approved, monitoring long-term safety and effectiveness in real-world use.

Contact this trial

Principal Investigator: Liffert Vogt, prof. dr., Amsterdam University Medical Centre

Phone: +31503616161

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 4
Registry
ClinicalTrials.gov
Start date
1 April 2024
Est. completion
1 December 2026

Where this trial is recruiting

🇳🇱 Netherlands

Primary endpoints

Albumin-creatinine ratio (ACR)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 13 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov