Study
Recruiting Not a phased study
This trial at a glance
Where this trial is running
| Site | City | State or country | Status at this site |
|---|---|---|---|
| Royal Adelaide Hospital | Adelaide | SA | Recruiting |
voxsanity.com.au · trial sites from public registries · registry record synced 11 October 2026 · not medical advice
Who can join
The official eligibility criteria
Registry text, reproduced exactly. These are the words the trial's sponsor published on ClinicalTrials.gov. They have not been edited, shortened or rewritten, and they are written for researchers rather than for patients.
1. Population - Group 1. Healthy co-habitants (n = 30)
Inclusion criteria:
* Household co-habitant of transplant recipient in trial
* Aged \>50 years
* Previous documented infection with VZV (known infection history or positive VZV IgG result)
Exclusion criteria:
* Aged \<50 years
* Unable or unwilling to provide informed consent to participate in the trial
* Known allergy to or intolerance of the contents of the RZV vaccine
* No previous infection with VZV (chickenpox)
* History of primary immunodeficiency, documented vaccine hypo-responsiveness, or active immunosuppressive therapy
2. Population - Groups 2-4. Transplant recipients (n = 90)
Inclusion criteria:
* Organ transplant recipients
\-- Specific immunosuppression regimen
* Tacrolimus, mycophenolate, prednisolone (n = 30, Group 2)
* Tacrolimus, mTORi, prednisolone (n = 30, Group 3)
* mTORi, mycophenolate, prednisolone (n = 30, Group 4)
* Aged \>18 years
* estimated GFR \> 15 mL/min/1.73m2
* Previous documented infection with VZV (known infection history or positive VZV IgG result)
Exclusion criteria:
* Aged \<18 years
* Unable or unwilling to provide informed consent to participate in the trial
* No previous infection with VZV (chickenpox)
* Known allergy to or intolerance of the contents of the RZV vaccine
* Current pregnancy
3. Population - Group 5. Other (n = 10)
Inclusion criteria:
* Immunosuppressed patient receiving single-agent rapamycin immunosuppression
* Aged \>18 years
* Previous documented infection with VZV (known infection history or positive VZV IgG result)
Exclusion criteria:
* Aged \<18 years
* Unable or unwilling to provide informed consent to participate in the trial
* Known allergy to or intolerance of the contents of the RZV vaccine
* No previous infection with VZV (chickenpox)
* Known allergy to or intolerance of the contents of the RZV vaccine
* Current pregnancy
* History of primary immunodeficiency, documented vaccine hypo-responsiveness, or active immunosuppressive therapy
4. Population - Group 6. Dialysis group (n = 30)
Inclusion criteria:
* Kidney failure receiving haemodialysis as kidney replacement therapy
* Aged \>18 years
* Previous documented infection with VZV (known infection history or positive VZV IgG result)
Exclusion criteria:
* Aged \<18 years
* Unable or unwilling to provide informed consent to participate in the trial
* Known allergy to or intolerance of the contents of the RZV vaccine
* No previous infection with VZV (chickenpox)
* Known allergy to or intolerance of the contents of the RZV vaccine
* Current pregnancy
* History of primary immunodeficiency or active immunosuppressive therapy
Dates on the record
Results, publications and the official record
- No results are posted on the official record yet.
- No publications are listed on the official record yet.
- Official record and contacts on ClinicalTrials.gov – contact details for each site are kept there, and are not copied onto this page.
Sources and dates
- ClinicalTrials.gov – the record this page reformats
- ClinicalTrials.gov processing date: 9 April 2026.
- This page last checked by Voxsanity: 11 October 2026.
Voxsanity reformats data from public registries into this layout. It does not edit, interpret or add to what the registry published.
Not medical advice.
Individual trial records are refreshed on a rolling basis rather than all at once, so a record may be up to several weeks old. Each trial page and trial card shows the date its own record was last synced. Where a record has lagged, its status, sites and enrolment can differ from the current registry state in either direction, so check the registry link on the trial page before acting on them.
Letter for your doctor
A one-page summary of this trial to print or email to your GP. It carries the registry's own record of the trial and its eligibility criteria, and nothing Voxsanity has written about whether it suits you.