Phase 2 Muscular Dystrophy Trial, Recruiting NCT06300307 Sponsor: ARTHEx Biotech S.L. Condition: Muscular Dystrophy
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Phase 2 Muscular Dystrophy Trial, Recruiting

NCT06300307
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been officially diagnosed with a condition called Myotonic Dystrophy Type 1 (DM1), confirmed by a genetic blood test showing more than 150 repeats of a specific gene change
  • You are able to walk on your own and can complete a 10-meter walk or run test without using aids like canes, walkers, or leg braces — though ankle-foot braces (worn around the ankle and foot) are allowed
  • You experience muscle stiffness (called myotonia) in your grip that lasts for more than 3 seconds, as confirmed by a specialist reviewer

Who may not be able to join:

  • People who were born with DM1 (known as congenital DM1, meaning symptoms were present from birth)
  • People who have significant weakness in the muscle at the front of the lower leg (shin area), or too much muscle loss there to safely perform a small muscle tissue sample (biopsy)
  • People who have taken mexiletine or any other medication used to treat muscle stiffness (myotonia) within roughly the past 3 weeks or longer, depending on the specific medication (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: +34676229821

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
ARTHEx Biotech S.L.
Registry
ClinicalTrials.gov
Start date
15 October 2024
Est. completion
1 July 2027

Where this trial is recruiting

🇨🇦 Canada 🇫🇷 France 🇮🇹 Italy 🇳🇱 Netherlands 🇪🇸 Spain 🇬🇧 United Kingdom 🇺🇸 United States

Primary endpoints

Incidence of adverse events

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov