Phase 1 Tuberculosis Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You are 3 years of age or older
- You have been diagnosed with active tuberculosis (TB) in the lungs that can be treated with the antibiotic rifampin, confirmed by a lab test (or, for young children who cannot cough up a sample, diagnosed using standard medical guidelines)
- You are starting a standard four-drug TB treatment plan that includes isoniazid, rifampin, pyrazinamide, and ethambutol
- You (or your parent/guardian) are able to give written permission to participate, and children aged 7 and older must also agree to take part
- You are willing and able to follow all the steps of the trial for its full duration
- You live within a specific local area that allows you to attend follow-up visits at a TB clinic
Who may not be able to join:
- You have trouble controlling your bladder (urinary incontinence), as this could make urine collection difficult
- You produce very little urine, as this could affect how urine samples are collected and measured
- You have reduced kidney function (confirm with trial site for specific test results)
- You have severe anemia, meaning your blood has very low levels of hemoglobin (confirm with trial site for specific test results), since blood draws are part of the trial
- Your liver enzyme levels are significantly elevated, based on a blood test (confirm with trial site for specific levels)
- You are pregnant or could become pregnant without using a highly effective form of birth control — a pregnancy test will be done at the start of the trial for those who could potentially become pregnant
- You weigh less than 10 kg (approximately 22 pounds)
- You are currently taking another medication that is known to interact significantly with TB treatment drugs
- You drink alcohol heavily — for example, more than 14 drinks per week or more than 4 drinks in a day if male, or more than 7 drinks per week or more than 3 drinks in a day if female (or as judged by the trial doctor)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: 4342439064
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Rifampin serum area under the concentration time curve for the 24 hour dosing interval; Adverse events
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.