Phase 2 Interstitial Lung Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are willing and able to understand and sign a consent form, and able to follow the study requirements
• You are willing to follow all study procedures and are available for the full length of the study
• You are male or female and over 18 years old
• A doctor has diagnosed you with Idiopathic Pulmonary Fibrosis (IPF) or another progressive lung scarring condition (ILD)
• Your lung function test results meet specific minimum levels — your DLCO is above 30% and your FVC is above 45% (confirm with trial site)
• If you are of reproductive age and sexually active with a partner of the opposite sex, you must use an approved form of contraception, such as condoms, diaphragm, IUD, or hormonal birth control
• You agree to follow certain lifestyle guidelines throughout the study

Who may not be able to join:

• You are currently on the waiting list for a lung transplant
• You need extra oxygen while resting
• You currently have an active respiratory infection or a sudden worsening of your lung fibrosis
• You have been diagnosed with celiac disease, or have a wheat or gluten allergy
• You have cirrhosis or active liver disease, or your liver function blood test results are more than twice the normal level (confirm with trial site)
• You have a history of inflammatory bowel disease, trouble swallowing, or a condition that affects the food pipe (such as achalasia)
• You have significant kidney problems, specifically a kidney function score (eGFR) below 40 ml/min (confirm with trial site)
• Your heart's electrical activity (measured by an ECG) shows certain abnormalities, including a QTcF reading above 450ms, or other findings that the study doctor considers a safety concern
• You currently have a problem with alcohol or illegal drug use
• You are pregnant, breastfeeding, or trying to become pregnant
• If you can become pregnant, you must use effective birth control (such as an IUD, hormonal implant, birth control pills, injections, patches, or vaginal rings) to participate
• If you are male and your partner could become pregnant, you must also agree to use effective birth control during the study
• You have a known allergy to the study drug (hymecromone) or any of its ingredients
• You regularly take certain medications known to interfere with how the study drug is processed in the body — specifically canagliflozin, temazepam, or tacrolimus
• The study doctor has concerns that you may not be able to follow the study plan
• You are currently taking part in another clinical treatment trial for ILD (though you may be eligible 12 weeks after finishing another trial)
• Your dose of other ILD medications has changed in the 3 months before the study start date
• You have any physical or mental health condition that the study doctor believes could put you at greater risk of harm

Important: Always verify eligibility with the trial site directly before applying.