Non-Alcoholic Fatty Liver Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
You are between 18 and 70 years old
You are not currently pregnant or breastfeeding
Your weight has been stable and you have not been doing regular exercise before joining the trial
You do not smoke or use tobacco products, drink excessive amounts of alcohol, or take dietary supplements or medications that might affect your blood sugar or fat levels (with some exceptions for people in the type 2 diabetes group)
You do not have serious problems with major organs or serious illnesses such as severe kidney disease or cancer
You also must fit into one of these four specific groups:
Lean group: You have a healthy body weight (BMI between 18.5 and 24.9), normal liver fat levels, and normal blood sugar results across all tests
Metabolically normal obesity group: You have obesity (BMI between 30 and 44.9) but have normal liver fat levels and normal blood sugar results across all tests
Obesity with insulin resistance and fatty liver group: You have obesity (BMI between 30 and 44.9), higher than normal liver fat, and blood sugar results that are slightly above normal but not yet at diabetes level
Obesity with type 2 diabetes group: You have obesity (BMI between 30 and 44.9) and have been diagnosed with type 2 diabetes, or your blood sugar test results fall in the diabetes range
Who may not be able to join:
- Anyone who does not meet all of the inclusion criteria listed above (confirm with trial site)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Bettina Mittendorfer, University of Missouri-Columbia
Phone: (573) 882-7619
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Insulin sensitivity assessed as insulin-mediated glucose disposal during a hyperinsulinemic-euglycemic clamp procedure.; 24-hour plasma glucose concentration; Macrophage isolation in adipose tissue biopsy; Macrophage isolation in skeletal muscle tissue
Can't join this trial?
Data last synced from ClinicalTrials.gov: 16 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.