PTSD Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are between 15 and 18 years old (inclusive)
• You are able to lie still on your back for up to 1 hour
• You are not pregnant and do not become pregnant during the study
• You agree to tell the research team about any urgent medical situations within 48 hours of them happening
• You agree not to join any other interventional clinical trials while this study is ongoing
• You are willing to follow all study procedures
• You agree to have your study visits recorded by video and/or audio (recordings are deleted within one month of the visit)
• A parent or guardian is willing to take part and provide consent on your behalf
• You speak and read English fluently or as your main language

If you are in the PTSD or trauma-exposed group, you also need to:

• Have experienced at least one traumatic event (as defined by medical guidelines), such as physical or sexual abuse, witnessing violence, a serious accident, a natural disaster, or the death of a close family member
• If joining as someone with PTSD: currently meet the full criteria for severe PTSD, confirmed through a clinical interview

Who may not be able to join:

• Your parent/guardian or you are unable or unwilling to give proper consent
• The research team believes you are likely to be exposed to further serious trauma, do not have enough social support, or do not have a stable living situation during the study
• The lead researcher feels, based on screening, that the study would not be suitable for you for any reason
• You have taken part in a clinical study involving an experimental drug in the last 30 days
• You have a medical reason why you cannot have an MRI scan (confirm with trial site)
• You experience claustrophobia (fear of enclosed spaces) or cannot lie still in the MRI scanner, even after practice sessions
• You are currently considered to be at serious risk of suicide (though a past history of suicide attempts does not automatically exclude you)
• You are considered a serious risk to others, based on a clinical interview
• You have been diagnosed with autism spectrum disorder
• You have an intellectual disability (IQ below 70, based on self-report)
• You currently have a medical condition that would prevent you from taking part
• You have had a traumatic brain injury and are still experiencing symptoms such as headaches, vision problems, or difficulty concentrating
• You have a neurological condition such as seizures, epilepsy, or a brain tumour (note: Tourette's disorder does not exclude you if you are in the PTSD or trauma-exposed group)
• You are currently using medications or substances, including alcohol, in a way that may affect your sleep
• There is a possibility you may be pregnant

Additional exclusions if you are in the typically developing (no trauma) group:

• You have a current or past mental health diagnosis (with the exception of a past specific phobia)
• You currently have a diagnosed sleep disorder (based on self-report)
• You have any history of traumatic experiences as defined by medical guidelines, including exposure to domestic violence, neglect, or emotional abuse

Additional exclusions if you are in the PTSD group:

• You have a current diagnosis or history of a psychotic disorder, bipolar disorder, or autism spectrum disorder (confirmed by clinical interview)

Additional exclusions if you are in the trauma-exposed (but not PTSD) group:

• You currently have PTSD, or have a current diagnosis or history of a psychotic disorder, bipolar disorder, or autism spectrum disorder (confirmed by clinical interview)

Important: Always verify eligibility with the trial site directly before applying.