Phase 2 Leukaemia Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 16 years or older
• People who have been diagnosed with acute myeloid leukemia (AML) and whose disease has been classified as "favorable-risk" according to a standard medical guideline called ELN 2022
• People whose AML went into remission after initial treatment and who have completed at least 3 rounds of a specific type of intensive follow-up (consolidation) chemotherapy, with very low or undetectable levels of leukemia remaining in the body (the exact definition of "very low" depends on the type of AML — confirm with trial site)
• People who have not had a stem cell transplant before joining the trial
• People who are reasonably active and able to carry out daily activities, as measured by a standard scale called ECOG (scores 0–2)
• People whose expected survival is at least 3 months
• People without serious heart, lung, liver, or kidney disease
• People who are able to understand the trial information and are willing to sign a consent form

Who may not be able to join:

• People whose leukemia has relapsed (come back) in the blood before enrolling
• People who have had an allergic reaction to the study drug or to drugs with a similar chemical make-up
• Women who are pregnant or breastfeeding, and women of childbearing age who are not willing to use effective contraception during the trial
• People with an active infection at the time of enrolment
• People with active (ongoing) bleeding
• People who have had a blood clot, blockage in a blood vessel, brain bleed, or similar condition within the past year
• People with a mental health condition or other circumstance that would prevent them from giving informed consent or following the trial's requirements
• People with significantly abnormal liver function test results or kidney function results, based on specific blood test thresholds (confirm with trial site)
• People with a history of certain heart conditions, including a notably prolonged heart rhythm interval (QTc), certain irregular heartbeats, a significant degree of heart block, a heart attack within the past year, heart failure, or coronary heart disease requiring medication
• People who have had surgery on a major organ within the past six weeks
• People with a history of drug abuse or long-term heavy alcohol use that could affect trial results
• People who have received an organ transplant (other than a bone marrow transplant)
• People whom the trial doctor considers unsuitable for the study for any other reason

Important: Always verify eligibility with the trial site directly before applying.