Phase 2 PTSD Trial, Recruiting NCT06386003 Sponsor: Unity Health Toronto Condition: PTSD
Back to Ptsd

Phase 2 PTSD Trial, Recruiting

NCT06386003
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with PTSD (according to standard psychiatric guidelines) for at least 6 months, as confirmed by a study psychiatrist
  • People whose PTSD symptoms are rated as moderate to severe based on a standardised assessment score of 50 or higher
  • People who are willing to avoid taking any psychiatric medications for the entire duration of the study

Who may not be able to join:

  • People who are pregnant, breastfeeding, or who are capable of becoming pregnant and are not using an effective form of contraception
  • People who have ever been diagnosed with, or currently have, a primary diagnosis of psychosis, schizophrenia, delusional disorder, borderline personality disorder, schizoaffective disorder, bipolar disorder, or dissociative identity disorder
  • People who have a history of, or currently have, heart artery disease, blood vessel disease affecting the brain or limbs, liver disease with abnormal liver test results, or any other medical condition that the investigator considers would significantly increase the risks of participating
  • People who have high blood pressure measuring 140/90 or higher on three separate occasions, using standard American Heart Association guidelines
  • People who have a history of seizures or epilepsy
  • People who have diabetes requiring insulin that is not well controlled
  • People who have had a stroke, a bleed in or around the brain, a heart attack, or a significant heart rhythm problem within the past year
  • People who have liver disease (with the exception of those who had Hepatitis C without symptoms and have already been successfully treated for it)
  • People who have ever experienced a psychotic episode caused by substance use
  • People who have ever had a substance use disorder specifically involving hallucinogens
  • People who have had an alcohol use disorder within the past 3 months

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 416-360-4000

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Unity Health Toronto
Registry
ClinicalTrials.gov
Start date
1 June 2026
Est. completion
1 January 2027

Where this trial is recruiting

🇨🇦 Canada

Primary endpoints

Feasibility and tolerability

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov