Endometrial Cancer Trial, Recruiting NCT06394297 Sponsor: Fundacao Champalimaud Condition: Endometrial Cancer
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Endometrial Cancer Trial, Recruiting

NCT06394297
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People diagnosed with cervical cancer that is considered suitable for treatment with a combination of radiation and chemotherapy aimed at curing the disease.
  • People whose biopsy has confirmed one of three specific cancer types in the cervix: squamous-cell carcinoma, adenocarcinoma, or adeno-squamous cell carcinoma.
  • People who have had a pelvic MRI scan performed.
  • People who have had both an MRI scan and a PET-CT scan of the abdomen and the area behind the abdominal organs (retroperitoneal space) done at the time of diagnosis.
  • People whose cancer is classified as stage IIB to IVA according to international gynaecological cancer staging guidelines (FIGO and TNM).
  • People who have had a planning MRI scan done with the radiation applicator in place, as required for the SBRT boost treatment.
  • People whose cancer has spread to lymph nodes in the retroperitoneal area, as long as those nodes are below the L1-L2 level of the spine (a specific anatomical landmark — confirm with trial site if unsure).
  • People who have signed the study-specific informed consent form.

Who may not be able to join:

  • People who have or have had another type of cancer, with the exception of very early-stage cervical cancer (carcinoma in situ) or a common, low-risk form of skin cancer (basal cell carcinoma).
  • People whose cervical cancer is a rare type, such as small cell neuroendocrine cancer, melanoma, or other uncommon cervical cancers.
  • People whose cancer has spread beyond the retroperitoneal lymph nodes above the L1-L2 spinal level (confirm with trial site).
  • People who have previously had radiation treatment to the pelvis or abdomen.
  • People who have previously had their uterus removed, either fully or partially (hysterectomy).
  • People who are unable to have an MRI scan for medical reasons.
  • People with a severe psychiatric condition.
  • People with serious, active health conditions in addition to their cancer.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 15 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Carlo Greco, MD, Fundaçao Champalimaud

Phone: +351210480200

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Fundacao Champalimaud
Registry
ClinicalTrials.gov
Start date
4 August 2023
Est. completion
4 August 2025

Where this trial is recruiting

🇵🇹 Portugal

Primary endpoints

Dosimetric Feasibility of SBRT boost; reproducibility of SBRT boost; Inter/intra fractional target motion; Adverse Events; Local control

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov