Transverse Myelitis Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You must be willing and able to sign a consent form before any study activities begin
• You must be a man or woman over 18 years of age
• You must have been diagnosed with neuromyelitis optica spectrum disorder (a condition affecting the nerves and spinal cord), have tested positive for a specific protein called Aquaporin-4 IgG, and currently be taking a commercially available medication called ravulizumab as prescribed
• Your level of physical disability must be below a certain threshold, meaning you are not severely disabled (confirm with trial site)

Who may not be able to join:

• You cannot participate if you are unable to tolerate or have any reason you cannot have an MRI scan
• You may not be able to join if you previously took a similar medication called eculizumab but stopped because it did not control your condition well enough, such as having a relapse or worsening shown on an MRI after at least 12 weeks of treatment
• You cannot join if you currently have an unresolved meningococcal infection (a type of serious bacterial illness)
• You cannot join if you have a history of an active infection (confirm with trial site for details)
• You cannot join if you are already taking part in another clinical trial for neuromyelitis optica spectrum disorder
• You cannot join if you are currently pregnant or breastfeeding

Important: Always verify eligibility with the trial site directly before applying.