Phase 2 PTSD Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who are currently serving in the military or who have previously served (veterans)
- People who have been experiencing at least one nightmare per week over the past month
- People who score at least 8 on a standard sleep difficulty questionnaire called the ISI (Insomnia Severity Index)
- People who are taking medication for PTSD, depression, anxiety, or sleep problems, as long as the dose has been stable for at least 8 weeks
Who may not be able to join:
- People who are at serious risk of suicide
- People with psychosis, bipolar disorder, or a current alcohol or drug use disorder
- People who have sleep apnea that has not been treated, or where treatment is not adequately managing the condition
- People who are currently using certain medications, including synthetic glucocorticoids, beta blockers, prazosin, or varenicline
- People who are currently receiving any form of therapy — either standard or experimental — that specifically targets nightmares, insomnia, or PTSD
- People who are unable to remember the content of their nightmares
- People who are unable to wear a wristband device or sync its data to a computer or phone
- People who are unable to have blood drawn as part of the study
- People who do not agree to having their DNA analysed from blood samples taken during the study
- People who do not agree to having their study visits audio recorded
- People who have REM sleep behaviour disorder or narcolepsy, as assessed by the study investigator
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: James C West, MD, Uniformed Services University of the Health Sciences
Phone: 240-620-4076
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Disturbing Dreams and Nightmare Severity Index; Insomnia Severity Index
Can't join this trial?
Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.