Phase 4 Tuberculosis Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 18 to 65 years old, of any gender
• People who have been diagnosed with pulmonary tuberculosis (TB affecting the lungs) according to a specific Chinese medical standard (WS 288-2017)
• People who have either never received TB treatment before, or have received standard first-line TB medication (HRZE) for less than one week
• People who show signs consistent with a Traditional Chinese Medicine pattern called "Qi and Yin deficiency," which includes at least two of these main symptoms — shortness of breath, tiredness, mental fatigue, or a weak pulse — plus at least one of these additional symptoms: coughing up blood, sweating without exertion, night sweats, poor appetite, bloating, or a red and tender tongue with thin coating
• People who are willing to participate voluntarily, are likely to take medications as directed, and have signed a consent form agreeing to take part

Who may not be able to join:

• People who have received similar Traditional Chinese Medicine treatment in the four weeks before joining the trial
• People whose TB has been found to be drug-resistant or extensively drug-resistant
• People with a known or suspected allergy or serious reaction to the trial drug or any of its ingredients, or who have a history of multiple allergies
• People whose test results have shown non-tuberculosis bacteria growing (on more than two occasions), or who have been diagnosed with a non-tuberculosis bacterial lung infection
• People with recurring TB, or people with a confirmed TB bacterial infection who have already received more than one week of TB treatment
• People who also have autoimmune diseases, cancer, serious blood disorders, epilepsy, or psychiatric conditions
• People with serious heart or brain blood vessel disease, such as severe heart failure, heart attack, or recent serious stroke (confirm with trial site)
• People with uncontrolled high blood pressure (blood pressure at or above 160/100 mmHg at the time of joining)
• People with poorly controlled diabetes
• People with serious liver or kidney disease, or abnormal liver or kidney blood test results above certain levels (confirm with trial site)
• People who have TB affecting parts of the body other than the lungs, such as lymph nodes, bones, kidneys, intestines, the nervous system, or the brain lining
• People who have other lung conditions such as lung cancer, cysts, abscesses, scarring of the lungs, or dust-related lung diseases
• People who are pregnant or breastfeeding
• People living with HIV, or people who test positive for syphilis
• People who have participated in another clinical trial within the past month (confirm with trial site regarding the exact timeframe)
• People with a history of alcohol or drug abuse, or any tendency toward dependence on substances
• People whom the research team considers unsuitable for the trial for any other reason

Important: Always verify eligibility with the trial site directly before applying.