Phase 4 PTSD Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged 18 to 70 years old who have had chronic nerve pain lasting 3 months or longer
- Both biological males and biological females are eligible
- Women of childbearing age may be eligible if they have no plans to become pregnant during the study period, agree to use contraception throughout the study, and agree to take pregnancy tests
- People who are Active Duty military, Veterans, or military retirees
- People who have not used ketamine in the past year
- People whose nerve pain is rated as moderate, scoring between 4 and 7 on a pain scale
Who may not be able to join:
- People with problems affecting thinking, memory, or mental processing
- People with a psychiatric condition that involves psychosis (losing touch with reality)
- People with a diagnosed neurocognitive disorder
- People who have had a Traumatic Brain Injury (TBI)
- People with active heart or cardiovascular disease, or high blood pressure that is not well managed
- People with thyroid disease that is untreated or not well controlled, including an overactive thyroid
- People with severe liver or kidney disease, or any level of kidney impairment
- People with a recent history of heart attack, vascular disease, or any other medical condition that a doctor considers to make ketamine unsafe for them
- People who are currently misusing substances
- People who are pregnant or breastfeeding
- People who are planning to become pregnant within 12 weeks of finishing treatment
- People with high blood pressure
- People with a known allergy or sensitivity to ketamine
- People with unstable blood pressure or circulation (confirm with trial site)
- People with slowed or difficult breathing
- People currently taking the medications Theophylline, Aminophylline, Sympathomimetics, Vasopressin, or Benzodiazepines
- People with a history of drug abuse or dependence, or who are currently at active risk of substance misuse
- People who are not able to follow the required steps before and after treatment, such as following food intake instructions, avoiding certain medications, staying at the clinic for at least 1 hour after treatment, and providing the name and contact number of someone who will provide a ride home after treatment
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: 210-473-7447
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Defense and Veterans Pain Rating Score (DVPRS); Brief Pain Inventory Scale (BPI); Life Satisfaction Questionnaire (LiSAT); Post-traumatic Stress Disorder Checklist (PCL-5); The Patient-Reported Outcomes Measurement Information System (PROMIS 29+2); Patient Health Questionnaire-9 (PHQ-9); Generalized Anxiety Disorder Scale
Can't join this trial?
Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.