Phase 2 PTSD Trial, Recruiting NCT06418178 Sponsor: Bronx VA Medical Center Condition: PTSD
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Phase 2 PTSD Trial, Recruiting

NCT06418178
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are U.S. military veterans aged 18 or older.
  • People who are able to give written informed consent.
  • People who are able to swallow pills.
  • People who agree to have study visits recorded, including therapy sessions and assessments.
  • People who can provide a contact person who is willing and able to be reached by the research team if needed.
  • People who can become pregnant must have a negative pregnancy test at the start of the study and before certain sessions, and must agree to use an adequate method of contraception.
  • People who have a current diagnosis of PTSD at both the screening and baseline stages.
  • People who agree not to participate in any other interventional clinical trials during the study.
  • People who commit to attending all required medication, therapy, and study procedures.

Who may not be able to join:

  • People who are not able to give proper informed consent.
  • People who have a medical history or screening findings that could make receiving a stimulant-type drug unsafe.
  • People who have uncontrolled high blood pressure.
  • People who have a significant medical or psychiatric condition in their history.
  • People who have active liver disease causing symptoms.
  • People who have a history of abnormally low sodium levels in the blood or episodes of dangerous overheating (confirm with trial site).
  • People who weigh less than 48 kilograms.
  • People who are unable or unwilling to safely reduce or stop certain psychiatric medications as required by the study.
  • People who are currently misusing illegal drugs or alcohol.
  • People who have received electroconvulsive therapy (ECT) or ketamine treatment within 12 weeks before enrolling.
  • People who are pregnant, breastfeeding, or able to become pregnant and are not using an effective method of contraception.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 20 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Rachel Yehuda, PhD, James J. Peters VA Medical Center

Phone: 718-584-9000

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Bronx VA Medical Center
Registry
ClinicalTrials.gov
Start date
3 June 2025
Est. completion
1 October 2029

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

PTSD Checklist for DSM-5 (PCL-5)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 20 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov