Phase 2 Leukaemia Trial, Recruiting NCT06420063 Sponsor: Essen Biotech Condition: Leukaemia
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Phase 2 Leukaemia Trial, Recruiting

NCT06420063
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People diagnosed with acute myeloid leukemia (a type of blood cancer) who are older than 6 months of age.
  • People whose leukemia cells have been confirmed to carry certain markers (called CLL-1, CD123, and/or CD33) through laboratory testing.
  • People who are in reasonably good general health, as measured by a standard health scoring system, with a life expectancy of more than 3 months.
  • People whose heart, liver, and kidneys are functioning well enough to meet specific laboratory test thresholds set by the trial (confirm with trial site for exact values).
  • People whose hemoglobin (a measure of red blood cells) is at or above a certain minimum level.
  • People who have no medical reasons preventing a cell collection procedure.
  • People who are able to understand the trial and are willing to sign a written consent form.

Who may not be able to join:

  • People with a serious illness or medical condition that would make it unsafe to follow the trial's treatment plan, including those with an active infection that is not under control.
  • People with an active bacterial, fungal, or viral infection that has not responded to treatment.
  • People with a known diagnosis of HIV, hepatitis B, or hepatitis C.
  • People who are pregnant or currently breastfeeding.
  • People who have taken steroid medications (glucocorticoids) as a whole-body treatment within the week before entering the trial.
  • People who, in the judgment of the trial doctors, may not be able to follow the trial's requirements.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: +12077706670

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Essen Biotech
Registry
ClinicalTrials.gov
Start date
10 July 2024
Est. completion
10 December 2025

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Incidence and severity of dose-limiting toxicities (DLTs) following chemotherapy preparative regimen and infusion of CD5/CD7 chimeric antigen receptor (CAR) T cells

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov