Phase 2 Lung Cancer Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You are 18 years old or older (male or female)
- You are in generally good physical condition and able to carry out everyday activities with little or no limitation
- You have been diagnosed with advanced or metastatic non-small cell lung cancer (a type of lung cancer) that cannot be removed by surgery, and/or has spread to other parts of the body
- Your cancer does not have certain specific genetic changes (called EGFR, ALK, ROS1, MET, HER2, RET, or BRAF mutations/fusions) — however, having a KRAS mutation is allowed (confirm with trial site)
- You have already been treated with both a type of immunotherapy (called an anti-PD-1 or anti-PD-L1 drug) and platinum-based chemotherapy, and your last dose was given more than 15 days before starting this trial
- Your cancer got worse within 6 months of starting the immunotherapy treatment
- You have already received all standard treatments available for your cancer
- Your cancer can be measured on scans using standard methods
- Your blood, kidney, and liver test results meet specific minimum levels of health, checked within 3 days before starting the trial (confirm specific values with trial site)
Who may not be able to join:
- You have a type of lung cancer called small cell lung cancer, or a mixed type that includes small cell lung cancer
- You have brain or spinal fluid involvement from your cancer that is causing symptoms — however, if brain spread causes no symptoms and requires no significant steroid medication, you may still be eligible (confirm with trial site)
- You have a weakened immune system, or you are taking steroid medication at a dose higher than the equivalent of 10mg of prednisone per day within 2 weeks before starting the trial (inhaled, nasal, or skin-applied steroids are allowed)
- You have received a live vaccine (a vaccine made from a live weakened germ) within the last 30 days
- You have had a fecal microbiota transplant (a procedure involving donor stool to change gut bacteria) within the last 3 months
- You have serious uncontrolled heart problems, such as heart failure, irregular heartbeat, unstable chest pain, or a heart attack or stroke within the last 6 months
- You have had a severe (grade 3 or higher) serious immune-related side effect from previous immunotherapy treatment
- You have a history of, or currently have, lung inflammation (pneumonitis) or scarring of the lungs (interstitial lung disease) that required steroid treatment
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Progression-free survival rate (PFS Rate) for the assessment of efficacy, defined as the rate of alive and non-progressive subjects as per iRECIST 1.1 over the study subjects.
Can't join this trial?
Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.