Early Phase 1 Non-Alcoholic Fatty Liver Disease Trial, Recruiting NCT06453915 Sponsor: University of California, Davis Condition: Non-Alcoholic Fatty Liver Disease
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Early Phase 1 Non-Alcoholic Fatty Liver Disease Trial, Recruiting

NCT06453915
Recruiting Early Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are 18 years of age or older
  • People who have had, or are planning to have, a liver biopsy as part of standard medical care for fatty liver disease with risk factors for a condition called MASH, OR as part of another clinical trial for MASH, OR as standard care before weight-loss (bariatric) surgery
  • The liver biopsy must take place within 6 months of the study-related scans
  • People who are able to give their informed consent to participate

Who may not be able to join:

  • People with a history of alcohol abuse, hepatitis B, hepatitis C, or any other chronic liver disease apart from non-alcoholic fatty liver disease
  • People with severe claustrophobia that is not controlled
  • People who weigh more than 225 kg, due to the limits of the scanning equipment
  • People who are pregnant or breastfeeding (a urine pregnancy test will be given before each PET/CT scan session to people aged 18–60 who could become pregnant, unless a documented hysterectomy is on record)
  • People who have taken part in another research study involving a PET scan for research purposes within the last 12 months
  • People who are currently imprisoned
  • People with any other health condition that, in the opinion of the study doctor, could affect the goals of the trial
  • People with an existing neurodegenerative disorder or dementia
  • People with a significant history of a major skull concussion or repeated head injuries
  • People who are currently taking blood-thinning (anticoagulant) medication
  • People who have metal implants (such as a pacemaker) or claustrophobia that would prevent them from having an MRI scan

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
Early Phase 1 studies are small, early exploratory studies that come before the main Phase 1 to 3 testing, so a standard phase success rate does not apply.

Contact this trial

Principal Investigator: Guobao Wang, PhD, UC Davis Health Department of Radiology

Phone: 916-734-7749

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Early Phase 1
Registry
ClinicalTrials.gov
Start date
30 April 2025
Est. completion
1 July 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

results of 18F-FDG scans compared with results of DPA-714 scans

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov