Rare Disease Trial, Recruiting NCT06478121 Sponsor: University of Exeter Condition: Rare Disease
Back to Rare Disease

Rare Disease Trial, Recruiting

NCT06478121
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You must be able to understand and agree to take part in the study on your own (have the mental ability to give consent)
  • People of any sex, ethnicity, or location can take part
  • Group 1 (Cases): You may qualify if you have a specific gene change that affects the cells in your pancreas that produce insulin (called beta cells)
  • Group 2 (Controls): You may qualify if you do NOT have a gene change affecting your insulin-producing cells, and you are a similar sex, age (within 15%), and body weight (within a certain range) to someone in Group 1

Who may not be able to join:

  • You are not able to understand or agree to take part in the study on your own
  • You are younger than 6 years old or older than 99 years old
  • You have a cochlear implant (a hearing device implanted in your ear)
  • You have metal clips in your brain used to treat a blood vessel problem (aneurysm clips)
  • You have a device implanted in your body to stimulate your nerves
  • You have any implanted heart device, such as a pacemaker, defibrillator, or heart monitor
  • You have a metal heart valve
  • You have a history of metal fragments in or around your eyes
  • You have any other implanted metal device that would make an MRI scan unsafe (confirm with trial site)
  • You experience severe anxiety in small or enclosed spaces (claustrophobia)

Note: The last several points above relate specifically to those who may need an MRI scan as part of the trial.


Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Andrew Hattersley, FRS, FMed, University of Exeter

Phone: +44 (0) 1392 408277

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
University of Exeter
Registry
ClinicalTrials.gov
Start date
11 November 2025
Est. completion
28 February 2029

Where this trial is recruiting

🇬🇧 United Kingdom

Primary endpoints

Identification and description of biomarkers or cellular features associated with specific rare causal genetic variants.; Identification of alterations in physiological function with specific rare genetic variants.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov