Phase 2 Migraine Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged between 18 and 64 years
- People who have given written consent to participate
- People diagnosed with chronic migraine according to established international diagnostic guidelines (ICHD-3)
- People who have had at least 15 headache days per month, including at least 8 migraine days per month, over the past 3 months — and this pattern must also be confirmed through a headache diary before the treatment phase begins
- People whose migraines first started at least one year before joining the trial, based on medical records or a detailed headache history review
- People whose migraines first began before the age of 50
- People who are not using any other migraine prevention medications during the study
- Women who could become pregnant must not be pregnant, must not be planning a pregnancy during the study, and must be using a highly effective form of contraception
Who may not be able to join:
- People with medication overuse headache who need a detox program from acute medications such as triptans or opioids — although an exception may be considered for those who have already completed at least 2 months without those medications and whose opioid use is 8 days per month or fewer (confirm with trial site)
- People who are pregnant, planning to become pregnant, unable to use contraception, or currently breastfeeding
- People with signs or a history of liver bile flow problems (cholestasis), reduced liver function, or reduced kidney function
- People with serious other health conditions or significant frailty that could reduce life expectancy or lead to a likely hospital stay, as assessed by the trial doctor
- People who have a known allergy or sensitivity to statin medications, or who have taken statins before
- People with a history of a condition called angioneurotic oedema (a type of severe swelling, often of the face or throat)
- People who have recently stopped a migraine prevention medication less than 4 weeks before the study starts, or stopped botulinum toxin (such as Botox) less than 16 weeks before the study starts
- People currently taking antiviral medications for hepatitis C
- People with a significant psychiatric illness
- People with dependence on alcohol or illicit drugs
- People who are unable to understand the study procedures or follow them for the full duration of the trial
- People being treated for an underactive thyroid (hypothyroidism)
- People with lactose intolerance
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Marte-Helene Bjørk, Professor, Haukeland University Hospital
Phone: 0047 41419596
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Number of migraine days
Can't join this trial?
Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.