Lung Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are 18 years of age or older
• You have been diagnosed with locally advanced or spreading (metastatic) non-small cell lung cancer (NSCLC) that has tested positive for an ALK gene change, confirmed through a tissue or cell sample
• You have had a full scan assessment (including a CT scan of the chest and upper abdomen, and an MRI of the brain) before starting the study treatment
• Your general health and ability to carry out daily activities falls within an acceptable range (rated 0, 1, or 2 on a standard medical scale)

Who may not be able to join:

• You have had another active cancer in the last 2 years (with some exceptions, such as certain skin, cervical, thyroid, breast, or prostate cancers — confirm with trial site)
• You have previously been treated with a type of targeted drug called an ALK TKI as a preventative (adjuvant) therapy, unless your cancer spread more than one year after finishing that treatment
• You have already received any systemic treatment (such as chemotherapy or targeted therapy) for your lung cancer after it became metastatic
• You have taken certain medications or foods that strongly affect how the body processes drugs (known as strong CYP3A inhibitors, strong CYP3A inducers, or certain narrow therapeutic index P-gp substrates) within 12 days before starting the study drug (confirm with trial site)
• You have a medical or mental health condition that the study doctor believes could make participation unsafe or unsuitable for you
• You are pregnant (confirmed by a positive pregnancy test)
• You are breastfeeding, or you are a woman who could become pregnant and are unwilling or unable to use a highly effective form of contraception during the study and for at least 35 days after the last dose of the study drug
• You are a man who could father a child and are unwilling or unable to use a highly effective form of contraception during the study and for at least 97 days after the last dose of the study drug
• You are currently taking part in another clinical trial that involves an active treatment (observational studies may be acceptable — confirm with trial site)
• You are unable to give your own legal consent, or are under guardianship or protective custody
• You are not registered with the French social security system
• You do not agree to allow your personal data to be collected for the study
• You are unable or unwilling to attend scheduled appointments, follow-up visits, and complete all parts of the study as required
• You are unable to answer the study's questions due to language barriers, psychological, social, or geographical reasons
• You are a member of the research team running this trial, or a close family member of someone on the research team

Important: Always verify eligibility with the trial site directly before applying.