Phase 3 Head and Neck Cancer Trial, Recruiting NCT06492460 Sponsor: Sun Yat-sen University Condition: Head and Neck Cancer
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Phase 3 Head and Neck Cancer Trial, Recruiting

NCT06492460
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People diagnosed with head and neck squamous cell carcinoma (a specific type of cancer affecting the head and neck area) at Stage III or Stage IV
  • People who have already had surgery to remove the cancer, where the surgery showed either cancer had spread outside nearby lymph nodes in the neck, or the surgical edges were positive or too close to the cancer (meaning not enough healthy tissue was removed around the tumour)
  • People with no signs that the cancer has spread to distant parts of the body
  • People who are reasonably well and able to carry out daily activities, as measured by a standard health scoring tool called the Karnofsky scale (score above 70)
  • People whose blood cell counts fall within acceptable ranges — including white blood cells, red blood cells (haemoglobin), and platelets
  • People whose liver is functioning within normal ranges, based on specific blood test results
  • People whose kidneys are functioning well enough, based on a measure of how efficiently the kidneys filter the blood
  • People who have been informed about the study and have signed a consent form agreeing to take part

Who may not be able to join:

  • People younger than 18 or older than 70 years of age
  • People whose treatment goal is to manage symptoms rather than to treat the cancer directly (palliative treatment)
  • People who have previously received chemotherapy, except for chemotherapy given before surgery to shrink the tumour
  • People who have previously received radiation therapy
  • People who are pregnant or breastfeeding
  • People who have had a different type of cancer in the past
  • People with certain serious health conditions that could increase risk or affect their ability to follow the trial requirements, such as unstable heart disease requiring treatment, kidney disease, chronic hepatitis, poorly controlled diabetes, or a mental illness

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Lei Chen, M.D, Sun Yat-sen University

Phone: +862013570051477

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Registry
ClinicalTrials.gov
Start date
20 September 2024
Est. completion
20 September 2029

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Failure-free survival (FFS)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov