Lupus Trial, Recruiting NCT06527872 Sponsor: GlaxoSmithKline Condition: Lupus
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Lupus Trial, Recruiting

NCT06527872
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are willing and able to sign a consent form to take part in the study
  • You are male or female and aged 18 or older when you first started taking belimumab
  • You were prescribed belimumab (either as an injection under the skin or through a drip) to treat active lupus nephritis (lupus affecting the kidneys), alongside other standard treatments
  • You started taking belimumab between 6 and 24 months before joining this study
  • Your medical records from at least 12 months before you started belimumab are available to the research team
  • You have a confirmed diagnosis of lupus nephritis, proven by a kidney biopsy taken at any point before you started belimumab, and your diagnosis falls into one of these types: Class III (focal lupus nephritis, with or without Class V), Class IV (diffuse lupus nephritis, with or without Class V), or Class V (membranous lupus nephritis)

Who may not be able to join:

  • You were receiving kidney replacement treatment — such as dialysis or a kidney transplant — or had end-stage kidney disease when you started belimumab
  • You were taking another targeted lupus antibody treatment (monoclonal antibody), or a similar medication that affects the immune system, at the same time as starting belimumab
  • You were participating in a clinical trial (that involves a treatment or intervention) during the period the study is looking at
  • You were pregnant when you first started taking belimumab
  • You had already received a kidney transplant when you started belimumab
  • You are pregnant or planning to become pregnant at the time of joining this study

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: GSK Clinical Trials, GlaxoSmithKline

Phone: 877-379-3718

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Registry
ClinicalTrials.gov
Start date
4 October 2024
Est. completion
29 March 2029

Where this trial is recruiting

🇫🇷 France 🇮🇹 Italy 🇯🇵 Japan 🇺🇸 United States

Primary endpoints

Number of Participants Maintaining Renal Function (Less than Equal to [<=] 30 Percentage [%] Decline in Estimated Glomerular Filtration Rate [eGFR] from the Initiation of Belimumab) and Not Requiring Renal Replacement Therapy

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov