Phase 4 Uveitis Trial, Recruiting NCT06539481 Sponsor: Alimera Sciences Condition: Uveitis
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Phase 4 Uveitis Trial, Recruiting

NCT06539481
Recruiting Phase 4

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are between 6 and 17 years old (at the time of giving consent to join)
  • You have a non-infectious form of uveitis (inflammation inside the eye that is not caused by infection) affecting the middle or back of the eye, and it has come back at least once a year
  • Your uveitis in the affected eye has not been well controlled by standard treatments, either because of unpleasant side effects or because the treatments haven't worked well enough
  • You have been taking steroid tablets or other systemic (whole-body) treatments for at least 3 months during the past 12 months

Who may not be able to join:

  • You have had surgery inside the affected eye within the last 90 days before your screening appointment
  • You have a known allergy or sensitivity to the drug used in this trial (called fluocinolone acetonide, or ILUVIEN®) or any of its ingredients
  • You have a history of glaucoma (a condition causing pressure build-up in the eye) or high eye pressure in the affected eye, unless you have already had a specific surgical procedure to lower that pressure at least 90 days before screening and your eye pressure is now stable and in the normal range (confirm with trial site)
  • Your eye pressure has been higher than 25 mmHg, or has needed extra treatment, surgery, or hospitalisation, within the 4 weeks before the start of the trial, and the study doctor feels this would put you at unacceptable risk

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 4 trials study a drug that has already been approved, monitoring long-term safety and effectiveness in real-world use.

Contact this trial

Phone: 353 (0) 1 553 0215

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 4
Sponsor
Alimera Sciences
Registry
ClinicalTrials.gov
Start date
31 August 2024
Est. completion
15 July 2026

Where this trial is recruiting

🇩🇪 Germany 🇪🇸 Spain 🇬🇧 United Kingdom

Primary endpoints

Absence of cystoid macular oedema on Optical Coherence Tomography and a decrease from baseline in vitreous haze grade of ≥2 steps, or absence of vitreous haze.; Rate of cataract formation and Rate of IOP elevation

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov