Early Phase 1 Leukaemia Trial, Recruiting NCT06541444 Sponsor: Base Therapeutics (Shanghai) Co., Ltd. Condition: Leukaemia
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Early Phase 1 Leukaemia Trial, Recruiting

NCT06541444
Recruiting Early Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are between 18 and 75 years old.
  • You have been diagnosed with acute myeloid leukemia (AML) based on 2016 WHO standards, and either cannot receive standard treatments, or your AML has come back or stopped responding after at least 2 previous rounds of treatment.
  • Your leukemia has either returned in your blood or bone marrow after a period of remission, or it did not respond well to standard chemotherapy treatments (confirm with trial site for your specific situation).
  • You are generally well enough to carry out basic daily activities, rated 0–2 on a standard medical fitness scale (meaning you may have some symptoms but are not completely unable to care for yourself).
  • Your doctor expects you to live for at least 12 weeks.
  • Your major organs (such as your liver and kidneys) are working at a normal or near-normal level.

Who may not be able to join:

  • You have a specific type of leukemia called acute promyelocytic leukemia (APL).
  • You have a serious bleeding problem or your blood does not clot properly, or you are currently taking clot-dissolving medication.
  • You have active tuberculosis (TB), are currently being treated for TB, or were treated for TB within the past year.
  • You are living with HIV, or you have an active syphilis infection.
  • You have taken certain medications that suppress the immune system within 1 week before starting the trial (some exceptions apply — confirm with trial site).
  • You have received a live vaccine (such as certain flu, MMR, or yellow fever vaccines) within 2 weeks before starting the trial, or plan to receive one during the study.
  • You have taken part in another clinical trial and received an experimental treatment within the past 4 weeks.
  • You have taken certain immune-boosting medications (such as interferons or thymosin) within 2 weeks before starting the trial (some exceptions apply — confirm with trial site).
  • You have active hepatitis B (with a certain level of virus detected in your blood) or hepatitis C infection.
  • Your doctor has any other concern that makes them feel this trial would not be safe or appropriate for you.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
Early Phase 1 studies are small, early exploratory studies that come before the main Phase 1 to 3 testing, so a standard phase success rate does not apply.

Contact this trial

Principal Investigator: zhiguo Long, Shanghai Pudong Hospital

Phone: 13817651474

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Early Phase 1
Sponsor
Base Therapeutics (Shanghai) Co., Ltd.
Registry
ClinicalTrials.gov
Start date
1 July 2024
Est. completion
1 June 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Dose-Limiting Toxicity; Complete Response Rate (CRR)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov