PTSD Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Adults between 18 and 65 years of age.
• People who have been diagnosed with PTSD according to standard diagnostic criteria, with a symptom checklist score above 33.
• People who have not changed their psychiatric medications or supportive talk therapy in the month before their first visit, and for whom it is medically appropriate to keep that treatment stable for the whole trial.
• People who are able to understand what the study involves, agree to take part in writing, and follow the study procedures for its full duration.

Who may not be able to join:

• People who have a medical reason that makes brain stimulation treatment unsafe, such as metal fragments in the head, a history of seizures, a brain tumour, stroke, brain aneurysm, or multiple sclerosis.
• People who have had an active substance use disorder in the last 3 months, or whose current substance use puts them at increased risk or causes significant problems in daily life.
• People with dementia or another condition affecting thinking and memory that would prevent them from engaging in the treatment.
• People with a history or diagnosis of schizophrenia, schizoaffective disorder, delusional disorder, or another psychotic illness that would make safe participation in the trial not possible.
• People assessed as being at significant risk of suicide, as determined by the clinical team.
• People for whom obsessive-compulsive disorder (OCD) is their primary diagnosis (though people with some OCD symptoms alongside PTSD may still be considered).
• People who cannot stop taking medications that significantly lower the seizure threshold, such as certain older antidepressants or clozapine.
• People who are currently pregnant, planning to become pregnant, or where pregnancy is suspected.
• People with unstable medical conditions that could make it unsafe to receive the brain stimulation treatment used in this trial.
• People with a severe traumatic brain injury.
• People who do not speak English, as rapid communication during treatment delivery is required for safety.
• People involved in significant ongoing legal cases or compensation claims that the research team determines could affect the study, particularly where mental health is being assessed as part of those proceedings.
• People who have previously received active brain stimulation (TMS) to specific areas of the front of the brain, or who have previously had electroconvulsive therapy (ECT).

Important: Always verify eligibility with the trial site directly before applying.