Phase 3 Vitiligo Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You have been diagnosed with a specific type of vitiligo called "nonsegmental vitiligo," with patches covering at least 0.5% of your face and at least 3% of other parts of your body.
• The total area of vitiligo on your body does not cover more than 10% of your skin.
• You have some hairs within the vitiligo patches on your face that still have their natural color (not white).
• You are willing to stop using any current vitiligo treatments from the start of the study until the final follow-up visit.
• If you are sexually active and past puberty, you are willing to avoid becoming pregnant or getting someone pregnant from the start of the study until 30 days after your last use of the study cream.

Who may not be able to join:

• You have been diagnosed with a different type of vitiligo, such as segmental vitiligo.
• You have another skin condition that causes loss of skin color, such as piebaldism, leprosy, or a fungal skin infection (confirm with trial site).
• You have another skin condition that, in the doctor's opinion, would interfere with applying the study cream or completing the study assessments.
• You have previously used or are currently using skin depigmentation treatments, such as monobenzone.
• You have a serious illness or physical, medical, or mental health condition that the doctor believes could interfere with your ability to fully participate in the study or could put you at risk.
• You have recently used certain treatments that fall within a required "washout period" before the study begins (confirm specific treatments with trial site).
• You currently use or have ever used a type of medication called JAK inhibitors, whether as a pill, injection, or cream.
• Your blood test results at the start of the screening show certain abnormal values as defined by the study rules (confirm with trial site).
• Your body mass index (BMI) falls below the 5th percentile or at or above the 85th percentile for your age group, based on a standard CDC calculator for children and teens.
• You are currently pregnant, breastfeeding, or planning to become pregnant during the study period.
• The doctor does not believe you will be able to follow the schedule for applying the cream and attending all required study visits.
• You live with someone who is currently participating in another study involving the same study cream (ruxolitinib cream) sponsored by the same company.
• You are an employee of the company running the trial or of the study doctor, or you are a dependent of either.
• You have a known allergy or reaction to any ingredient in the study cream.

Important: Always verify eligibility with the trial site directly before applying.