Phase 2 Lupus Trial, Recruiting NCT06559163 Sponsor: Zenas BioPharma (USA), LLC Condition: Lupus
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Phase 2 Lupus Trial, Recruiting

NCT06559163
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 18 to 70 years old (male or female)
  • People who were diagnosed with lupus (SLE) at least 24 weeks before the screening visit, and whose diagnosis meets a recognised international classification system for lupus
  • People whose lupus is currently active enough to meet specific disease activity scores measured at the screening visit and at the start of the trial (confirm with trial site for exact score details)
  • People whose lupus is active enough that, in the opinion of the doctors running the trial, it is appropriate to enter them into a study using an investigational treatment
  • People who are already being treated with at least one standard lupus medication, such as oral steroids, antimalarial drugs, and/or immunosuppressant medications

Who may not be able to join:

  • People with active lupus kidney disease (lupus nephritis) where, in the doctors' opinion, current medications are not sufficient to keep the person safe, or where additional treatments not allowed in the trial would be needed
  • People who have had a blood clot (in a vein or artery) in the past 6 months, or within the past 12 months if it was linked to antiphospholipid syndrome or another condition that increases clotting risk
  • People who have an active skin condition other than lupus-related skin disease (for example, psoriasis or certain other inflammatory skin conditions) that could make it difficult to assess lupus skin symptoms
  • People with severe active lupus affecting the brain or nervous system
  • People who have another active inflammatory condition besides lupus (such as rheumatoid arthritis, psoriatic arthritis, or similar conditions) that could interfere with assessing lupus symptoms, in the opinion of the trial doctors

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 833-269-4696

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Zenas BioPharma (USA), LLC
Registry
ClinicalTrials.gov
Start date
17 September 2024
Est. completion
1 June 2026

Where this trial is recruiting

🇧🇪 Belgium 🇧🇬 Bulgaria 🇨🇦 Canada 🇨🇳 China 🇩🇰 Denmark 🇩🇪 Germany 🇬🇷 Greece 🇮🇹 Italy 🇯🇵 Japan 🇲🇽 Mexico 🇵🇱 Poland 🇵🇹 Portugal Puerto Rico 🇷🇴 Romania 🇿🇦 South Africa 🇪🇸 Spain 🇹🇼 Taiwan 🇺🇸 United States

Primary endpoints

Primary Outcome Measure

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov