Spinal Muscular Atrophy Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

For people with a spine condition:

• You have been diagnosed with Ankylosing Spondylitis or a related spine condition called non-radiographic Spondyloarthritis, confirmed using standard medical criteria
• You are between 18 and 65 years old
• You are willing to give your consent to take part in the study

For healthy volunteers:

• You are a healthy person between 18 and 65 years old who can be matched by age and gender to a patient participant
• You are willing to give your consent to take part in the study

Who may not be able to join:

• You have been taking high-dose steroid medication (more than 5mg of prednisone per day for more than 3 months)
• You have certain other health conditions that can cause muscle loss, such as uncontrolled diabetes, chronic heart failure, thyroid or parathyroid disease, chronic kidney failure, or chronic liver failure
• You have a hand condition or injury that would affect your ability to have your grip strength measured accurately
• You are taking certain medications that can affect bone health, such as bisphosphonates, teriparatide, anticonvulsants, heparin, or blood thinners
• You have psoriasis or inflammatory bowel disease
• You have an active infection in the thigh area where an ultrasound scan would be carried out
• You weigh more than 100 kg, as this affects the bone density scanning equipment used in the study
• You are assessed as malnourished based on a short nutrition screening questionnaire (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.