Phase 2 Kidney Cancer Trial, Recruiting NCT06580002 Sponsor: University of California, Irvine Condition: Kidney Cancer
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Phase 2 Kidney Cancer Trial, Recruiting

NCT06580002
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People (male or female) who have been diagnosed with breast cancer and have received treatment such as chemotherapy, radiotherapy, surgery, or other breast cancer treatments.
  • People with a cancer other than breast cancer who received chemotherapy containing anthracyclines or platinum within the past 3 years.
  • People with a cancer other than breast cancer who received other types of cancer treatment within the past 3 years.
  • People aged 18 or older.
  • People who feel, or whose doctor feels, that their memory or thinking abilities have gotten worse since their cancer diagnosis or since starting cancer treatment.
  • People who are able to understand and agree to take part in the study (provide informed consent).
  • People who can read and write in English, Chinese, Korean, Vietnamese, or Spanish, in order to complete the study questionnaires.
  • People who are willing and able to complete questionnaires and computer-based assessments during the study. Note: People with vision problems or degenerative conditions (such as Parkinson's disease) may still be eligible if they can complete the questionnaires with assistance, even if they cannot complete the computer-based assessments (confirm with trial site).
  • People currently taking part in another research study may still be considered eligible, if the principal investigator judges that the two studies would not interfere with each other scientifically or medically.

Who may not be able to join:

  • People who have cancer that has spread to the brain (brain metastases).
  • People who are not willing to undergo the thinking and memory assessments required by the study.
  • Women who are currently pregnant, breastfeeding, or planning to become pregnant during the study period.
  • Women who could potentially become pregnant must have a negative pregnancy test at the screening stage if there is any suspicion of pregnancy. Women considered not able to become pregnant must have a history of being postmenopausal for at least one year, or have had a tubal ligation or hysterectomy (confirm with trial site).
  • People who have a known or suspected allergy to riluzole or any of its ingredients.
  • People who are currently taking, or planning to take, certain medications or substances that could interact with the study drug — these include pixantrone, abametapir, cannabis, capmatinib, lapatinib, methotrexate, levoketoconazole, or people who have smoked within the last month.
  • People with liver problems, specifically where certain liver enzyme levels (AST or ALT) are three or more times higher than the normal range.
  • People with serious existing medical conditions that the investigator believes would make participation in the study unsafe or unsuitable.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Alexandre Chan, PharmD, MPH, Chao Family Comprehensive Cancer Center

Phone: 1-877-827-8839

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
University of California, Irvine
Registry
ClinicalTrials.gov
Start date
2 December 2024
Est. completion
1 July 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change in circulating Brain-Derived Neurotrophic Factor (BDNF) levels over time in cancer survivors experiencing cognitive impairment (CRCI)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov