Cystic Fibrosis Trial, Recruiting NCT06595420 Sponsor: University of Virginia Condition: Cystic Fibrosis
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Cystic Fibrosis Trial, Recruiting

NCT06595420
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

Outpatient group (people with Cystic Fibrosis attending clinic):

  • People who have been diagnosed with Cystic Fibrosis
  • People who are older than 30 years of age
  • People who are able to give their own informed consent to participate

Inpatient group (people with Cystic Fibrosis admitted to hospital):

  • People who have been diagnosed with Cystic Fibrosis
  • People who are older than 7 years of age
  • People who are able to give informed consent, or assent where appropriate for their age
  • People who are in hospital due to a lung infection flare-up, either having had more than one hospital admission in the past 12 months, or no hospital admissions in the past 12 months
  • People who are able to provide a urine sample on their own

Healthy volunteer group:

  • People who consider themselves to be in good health (based on their own report)
  • People aged between 30 and 50 years old
  • People who are able to give their own informed consent to participate

Who may not be able to join:

Outpatient group (people with Cystic Fibrosis):

  • People who have had an organ transplant at any point
  • People who have a history of a weakened immune system
  • People who have been diagnosed with cancer, either in the past or currently
  • People who are pregnant or breastfeeding
  • People who are on ongoing dialysis
  • People who have attended fewer than 2 clinic visits in the 12 months before enrolling, as this may indicate difficulty keeping appointments

Inpatient group (people with Cystic Fibrosis):

  • People who have already started intravenous (drip) antibiotics in hospital before the first blood and urine samples are collected
  • People who have had an organ transplant at any point
  • People who have a history of a weakened immune system
  • People who have been diagnosed with cancer, either in the past or currently
  • People who are pregnant or breastfeeding
  • People who are on ongoing dialysis

Healthy volunteer group:

  • People who have or have had kidney disease, an organ transplant, cancer, or any other ongoing health condition
  • People who are currently taking antibiotics
  • People who are experiencing urinary symptoms such as pain when urinating, needing to urinate very often, or feeling a sudden urgent need to urinate
  • People who are pregnant
  • People who are menstruating on the day of their study visit
  • People who are a blood relative of someone with Cystic Fibrosis

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 434-924-0946

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
9 January 2025
Est. completion
1 December 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Examine whether trajectories of eGFR (calculated from serum creatinine and cystatin C) correlate with urinary kidney injury signatures detected in different urine fractions, or urinary neutrophil levels/activation.; Correlation between recurrent hospitalizations and urinary kidney injury signature.; Relationship between recurrent hospitalization and change in slope of eGFR

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov