Phase 3 Lung Cancer Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You are willing to sign a consent form and able to follow all the steps of the trial
- You are between 18 and 75 years old at the time of signing the consent form
- You have been confirmed (through a tissue or cell sample) to have stage 4 non-small cell lung cancer that does not have certain genetic mutations ("driver gene negative")
- You have at least one tumour that can be measured on a scan, assessed within 4 weeks before joining the trial
- You have a localised tumour that can be injected, located in the outer area of the lung, that is 5 cm or smaller in size — this could be the original tumour or one that has come back after surgery or radiotherapy
- You are in good general health and able to carry out daily activities (with little to no limitation) within 7 days before the local treatment
- Your localised tumour has remained stable (not grown or shrunk significantly) after two rounds of standard first-line chemotherapy and immunotherapy treatment
- You are expected to live for at least 3 months
- Your liver, kidney, heart, blood, and other body functions are within normal ranges
Who may not be able to join:
- You are planning to have radiotherapy, surgery, or similar treatments on the tumour after the injection
- You have serious heart or lung problems, advanced liver or kidney failure, dangerous heart rhythm problems, or high blood pressure
- You have serious bleeding problems, clotting disorders, active infections, or severe dehydration
- You have a blood disorder, an autoimmune disease, or cirrhosis of the liver
- You have a history of severe emphysema or significant damage to the air sacs in your lungs
- You have a known allergy or medical reason not to use toluene sulfonamide (the drug being studied) (confirm with trial site)
- You are pregnant, breastfeeding, or planning to become pregnant during the study
- The trial doctors have identified any other reason that makes you unsuitable for the trial
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Chengzhi Zhou, doctor, The First Affiliated Hospital of Guangzhou Medical University,Guangzhou
Phone: 13560351186
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Objective response rate(ORR)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 7 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.