Phase 2 Obesity Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 65 years or older
• People with a body mass index (BMI) between 30 and 45, or above 45 with a doctor's approval
• People whose weight has stayed relatively stable (no more than 5% change) over the past 6 months
• People who have been identified as having knee or hip osteoarthritis based on a specific questionnaire (the Roux questionnaire)
• People who live independently in their own home
• People who are not very physically active — meaning they are not doing regular strength training or more than 20 minutes of aerobic exercise on more than 2 days per week in the past 3 months
• People who do not have certain heart or physical safety concerns during exercise (such as chest pain, dizziness, or frequent falls) that would make exercise unsafe, based on a standard screening tool
• People who are not currently taking weight-loss medication (medication for diabetes management is allowed if weight has been stable)
• People who have been approved to take part by the trial's medical director
• People who are willing to give their consent and agree to take part in all study activities

Who may not be able to join:

• People currently living in a nursing home, rehabilitation facility, or assisted living environment
• People who have been treated with medication for a psychiatric condition other than depression or anxiety in the past year
• People with currently untreated or unstable depression or anxiety, identified through a standard questionnaire score above a certain threshold
• People who have been hospitalised for a psychiatric event in the past year
• People with a history of mild cognitive impairment or dementia
• People who score below a certain level on a standard telephone-based memory and thinking assessment
• People with hearing or vision difficulties that would prevent them from using video call software
• People with severe arthritis or another joint/muscle condition that makes walking unsafe
• People currently receiving treatment for a bone fracture
• People currently taking a weight-loss medication (diabetes medications are permitted if weight is stable)
• People with certain exercise safety concerns (such as chest pain, dizziness, or frequent falls) who have not received doctor approval
• People who have had a joint replacement or other orthopaedic surgery in the past 6 months
• People who have a joint replacement or other orthopaedic surgery planned within the next 18 months
• People with certain serious or uncontrolled health conditions, including uncontrolled high blood pressure; serious heart disease, stroke, or unstable chest pain within the past year; certain chronic lung diseases; any condition requiring oxygen use; neurological or blood disorders; active cancer treatment (except certain skin cancers); kidney failure requiring dialysis; significant difficulty with basic daily activities; or heavy alcohol use (more than 14 drinks per week)
• People currently taking part in another research study that involves an active intervention
• People who are unwilling or unable to follow the study requirements, including being randomly assigned to a group and using technology tools
• People who are unable or unwilling to attend three virtual testing appointments

Important: Always verify eligibility with the trial site directly before applying.