PTSD Trial, Recruiting NCT06629064 Sponsor: VA Office of Research and Development Condition: PTSD
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PTSD Trial, Recruiting

NCT06629064
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are fluent in English
  • People who have been diagnosed with Post-Traumatic Stress Disorder (PTSD) according to current diagnostic guidelines (DSM-5)
  • People who are willing to attend 8 remote (online) memory training sessions spread across four weeks
  • People who are willing to have two MRI brain scans — one before and one after the memory training
  • People whose medications and any mental health treatments have remained unchanged for at least 4 weeks before joining

Who may not be able to join:

  • People with a history of a psychotic disorder or bipolar disorder at any point in their life
  • People who have had a severe problem with drug or alcohol use in the past year (note: mild-to-moderate alcohol use disorder may still be allowed — confirm with trial site)
  • People with a history of a neurological condition that could affect thinking or memory, such as a stroke, brain surgery, a brain aneurysm, or a seizure disorder
  • People who are currently in crisis with serious thoughts of suicide that require immediate care
  • People with a moderate to severe traumatic brain injury (mild cases may still be eligible — confirm with trial site)
  • People who are currently taking benzodiazepines (a type of sedative/anxiety medication) or certain other medications that block a brain chemical called acetylcholine
  • People who cannot safely have an MRI scan, for example due to metal implants or certain medical devices in the body

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Daniel M Stout, PhD, VA San Diego Healthcare System, San Diego, CA

Phone: (858) 642-3944

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
1 October 2024
Est. completion
30 September 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Behavioral Threat Expectancy Ratings During Extinction Performance; Extinction Electrodermal Activity Response; Extinction Blood Oxygen Level Dependent (BOLD) Response

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov