Phase 2 Leukaemia Trial, Recruiting NCT06635681 Sponsor: Institute of Hematology & Blood Diseases Hospital, China Condition: Leukaemia
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Phase 2 Leukaemia Trial, Recruiting

NCT06635681
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People diagnosed with a type of blood cancer called Acute Myeloid Leukaemia (AML), or a related condition called AML with myelodysplastic syndrome features, based on recognised medical classification systems
  • People aged 14 to 60 years old (male or female)
  • People whose general physical health and ability to carry out daily activities falls within an acceptable range, as measured by a standard medical scoring system (a score of 0–2 on the ECOG scale)
  • People whose recent blood and heart test results (taken within 7 days before starting treatment) fall within acceptable ranges, including: liver function markers (bilirubin, AST, ALT), kidney function (creatinine), heart muscle enzymes, and a heart pumping strength (ejection fraction) of more than 50% on an ultrasound of the heart
  • People who are able to provide signed consent before any study procedures begin — or, where the patient's condition makes this difficult, consent may be signed by a legal guardian or close family member

Who may not be able to join:

  • People whose AML is a specific subtype known as Acute Promyelocytic Leukaemia with a PML-RARA genetic change
  • People whose AML involves a specific genetic change called BCR-ABL
  • People who have already received treatment for their AML (though limited prior use of hydroxyurea or low-dose cytarabine to reduce cancer cell levels may be acceptable — confirm with trial site)
  • People who currently have another active cancer in another part of the body that requires treatment
  • People with certain active heart conditions, including: poorly controlled or symptomatic chest pain (angina); a heart attack within the 6 months before joining; a heart rhythm problem that requires medication or causes significant symptoms; or poorly controlled or symptomatic heart failure above a mild level
  • People with serious ongoing infections, specifically unresolved tuberculosis or a fungal lung infection called pulmonary aspergillosis
  • People whom the trial researchers consider unsuitable for participation for other medical reasons (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 8 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Hui Wei, MD, Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College

Phone: 13132507161

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Institute of Hematology & Blood Diseases Hospital, China
Registry
ClinicalTrials.gov
Start date
29 September 2024
Est. completion
1 December 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Event-free survival (EFS)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 8 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov