Interstitial Lung Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You have been diagnosed with one of the following lung conditions: idiopathic pulmonary fibrosis (IPF), familial pulmonary fibrosis (FPF), another type of scarring lung disease (such as fibrotic hypersensitivity pneumonitis, a specific type called iNSIP, a lung disease linked to a connective tissue condition, or an unclassified scarring lung disease), or early lung abnormalities spotted on a scan (called interstitial lung abnormalities).
- Your lungs are working well enough to meet certain breathing test results during the screening period — specifically, your lung capacity (FVC) is at least 45% of what is expected, your airflow ratio (FEV1/FVC) is 0.7 or above, and your lungs' ability to transfer oxygen into the blood (DLco) is at least 40% of what is expected (confirm with trial site if unsure about your results).
- You are able to give written consent to take part in the study, as approved by an ethics committee.
- You are able to have a CT scan and complete breathing (lung function) tests.
- You are between 18 and 80 years old.
- You can understand Dutch or English.
Who may not be able to join:
- You have been diagnosed with a combination of pulmonary fibrosis and emphysema (CPFE).
- You have chronic obstructive lung disease (COPD) with an airflow ratio (FEV1/FVC) below 70%.
- You have severe asthma that is not well controlled.
- You currently have an active cancer, unless it is a low-risk skin cancer (squamous cell carcinoma), low-risk breast cancer, or low-risk prostate cancer.
- You are currently pregnant or breastfeeding.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Esther Nossent, MD, Amsterdam UMC, locatie VUmc
Phone: 0205668753
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Inflammatory and fibrosis extent assessed by HRCT; Pulmonary function tests (PFTs)- Spirometry volumes; Pulmonary function tests (PFTs)- DLCO measurement; Pulmonary function tests (PFTs)- Lungvolume measurement; Biomarkers related to pulmonary fibrosis will be measured in plasma and serum; Peripheral blood mononuclear cell (PBMC) populations in blood; Exhaled breath analysis including volatile organic compounds
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.