OCD Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have been diagnosed with obsessive-compulsive disorder (OCD) according to standard medical guidelines (DSM-5)
- People whose OCD is rated as severe, with a score of more than 27 on a recognised OCD severity scale (Yale-Brown Obsessive-Compulsive Scale)
- People who have had severe OCD symptoms and significant life impairment for more than 5 years, despite trying both medication and psychological treatment
- People who have tried at least two different medications that target serotonin (a brain chemical) and one additional supporting medication, without enough improvement
- People who have tried an adequate course of cognitive behavioural therapy (a structured talking therapy) without enough improvement, as assessed by the study psychiatrist
- People aged between 22 and 75
- People who are able to understand and sign a written consent form agreeing to take part
Who may not be able to join:
- People who have severe major depression that also includes psychotic features (such as hallucinations or delusions)
- People assessed as having a significant risk of suicide, based on a specific rating scale score
- People who also have a primary psychotic disorder, post-traumatic stress disorder (PTSD), or an eating disorder
- People who have had a problem with substance or alcohol misuse or dependence in the past 12 months
- People who show significant decline in memory or thinking ability, based on scores from two standard cognitive tests
- People who have another significant neurological condition or illness affecting brain function (a tic disorder would not automatically exclude someone — confirm with trial site)
- People whose pre-surgical brain scan (MRI) shows anything that the study neurosurgeon considers would make the surgical procedure unsafe
- People who have any condition or health factor that would make the type of surgery involved in this trial unsafe (confirm specific details with trial site)
- People who are pregnant
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Nader Pouratian, M.D., Ph.D., University of Texas Southwestern Medical Center
Phone: 2146486630
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Efficacy of amSTN stimulation on OCD symptoms as measured by YBOCS; Incidence of Adverse events
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.